منابع مشابه
Metal-Induced Oxidative Stress and Cellular Signaling Alteration in Animals
Contamination by heavy metals has attracted increasing attention considering the ability of these elements in producing serious consequence to ecosystem, and especially on animals health. Due to their widespread use in human activities such as industry, agriculture and even as medicine (e.g. arsenic, selenium and platinum), numerous health risks may be associated with exposure to these substanc...
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Despite its widespread biological importance, knowledge about the basic workings of the nitric oxide (NO) signaling pathway at the cellular level has been unsatisfactory. As reviewed here, recent findings have begun to rectify this deficiency. Elementary NO signals may be very discrete, being short lived (seconds or less), of low amplitude (peak concentration in the low nanomolar range), and co...
متن کاملstudy the effects of low level laser diode on no production and healing of diabetic and cortisone acetate and normal wounded sd rats
nitric oxide (no) is a small molecule synthesized by most of mammalian cells with diverse biological activities including vasodilatation, host defense and wound healing. impaired wound healing is a common occurrence among diabetics and patients receiving glucocorticoid therapy. on the other hand the application of laser in biomedical area have been increased. thus, the current studies were desi...
15 صفحه اولThe roles of EPIYA sequence to perturb the cellular signaling pathways and cancer risk
Abstract It was shown that several pathogenic bacterial effector proteins contain the Glu-Pro-Ile-Tyr-Ala (EPIYA) or a similar sequence. These bacterial EPIYA effectors are delivered into host cell via type III or IV secretion system, where they undergo tyrosine phosphorylation at the EPIYA sequences, which triggers interaction with multiple host cell SH2 domain-containing proteins and thereby...
متن کاملNo-signaling, intractability and entanglement
We consider the problem of deriving the no-signaling condition from the assumption that, as seen from a complexity theoretic perspective, the universe is not an exponential place. A fact that disallows such a derivation is the existence of polynomial superluminal gates, hypothetical primitive operations that enable superluminal signaling but not the efficient solution of intractable problems. I...
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ژورنال
عنوان ژورنال: Pflügers Archiv - European Journal of Physiology
سال: 2010
ISSN: 0031-6768,1432-2013
DOI: 10.1007/s00424-009-0765-9